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EU-Förderung (1.140.800 €): Pangenom-Graphalgorithmen und Datenintegration Hor08.10.2019 EU-Rahmenprogramm für Forschung und Innovation "Horizont"
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Pangenom-Graphalgorithmen und Datenintegration
Genomes are strings over the letters A,C,G,T, which represent nucleotides, the building blocks of DNA. In view of ultra-large amounts of genome sequence data emerging from ever more and technologically rapidly advancing genome sequencing devices—in the meantime, amounts of sequencing data accrued are reaching into the exabyte scale—the driving, urgent question is: how can we arrange and analyze these data masses in a formally rigorous, computationally efficient and biomedically rewarding manner? Graph based data structures have been pointed out to have disruptive benefits over traditional sequence based structures when representing pan-genomes, sufficiently large, evolutionarily coherent collections of genomes. This idea has its immediate justification in the laws of genetics: evolutionarily closely related genomes vary only in relatively little amounts of letters, while sharing the majority of their sequence content. Graph-based pan-genome representations that allow to remove redundancies without having to discard individual differences, make utmost sense. In this project, we will put this shift of paradigms—from sequence to graph based representations of genomes—into full effect. As a result, we can expect a wealth of practically relevant advantages, among which arrangement, analysis, compression, integration and exploitation of genome data are the most fundamental points. In addition, we will also open up a significant source of inspiration for computer science itself.
Geförderte Unternehmen:
| Firmenname | Förderungssumme |
| Cornell University | ? |
| 322.000 € | |
| Illumina Cambridge Ltd. | 0,00 € |
| Institut Pasteur | 147.200 € |
| 55.200 € | |
| UNIVERSITAET BIELEFELD | 289.800 € |
| Universita' Degli Studi DI Milano-Bicocca | 197.800 € |
| 128.800 € |
Quelle: https://cordis.europa.eu/project/id/872539
Diese Bekanntmachung wurde von Englisch nach Deutsch übersetzt. Die Bekanntmachung bezieht sich auf einen vergangenen Zeitpunkt, und spiegelt nicht notwendigerweise den heutigen Stand wider. Der aktuelle Stand wird auf folgender Seite wiedergegeben: Cornell University SCHOOL, Ithaca, USA.
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